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Uman Diagnostics multivariate data analysis
Multivariate Data Analysis, supplied by Uman Diagnostics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multivariate+analysis/analysis+image+multivariate+software/pm41702960-102-0-31
Average 86 stars, based on 1 article reviews
multivariate data analysis - by Bioz Stars, 2026-10
86/100 stars

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Article Title: Dynamic variations of plasma and urine metabolic profiles in left anterior descending coronary artery ligation-induced myocardial infarction rats and the regulatory effects of Chinese patent medicine Xin-Ke-Shu.
Article Snippet: Myocardial infarction (MI) is one of the most severe cardiovascular diseases (CVD).. Traditional Chinese medicines have unique advantages in the treatment of CVD, with Xin-Ke-Shu (XKS) being a commonly used Chinese patent medicine for the prevention and treatment of MI patients.. This study aimed to investigate the dynamic metabolic profiles of plasma and urine in left anterior descending coronary artery ligation (LAD) -induced MI rats at days 3, 12, and 21 after surgery, and to evaluate the regulatory effects of XKS at these time points using ultraperformance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/ MS) metabolomics.

Article Title: TiO 2 @COF-based solid-phase microextraction combined with UHPLC-MS/MS for the rapid determination of potential biomarkers of phosphatidylcholines and lysophosphatidylcholines in head and neck cancers.
Article Snippet: Phosphatidylcholine (PC) and lysophosphatidylcholine (LPC), two types of phospholipids (PLs), have been reported to be closely correlated with head and neck cancers of laryngeal cancer (LC) and thyroid cancer (TC), which make their analysis crucial.. TiO2@COF-based solid-phase microextraction (SPME) coupled to UHPLC-MS/MS was developed for the rapid and accurate detection of seven potential PL biomarkers from small amounts of serum in this work.. The combination of TiO2 and COF proves to be effective for the extraction of the target analytes.

Article Title: Integrated nutritional and functional components analyses reveal insights into the peel and pulp quality at different harvest times of 'Dahongpao' tangerine (Citrus reticulata Blanco).
Article Snippet: The fruit of Citrus reticulata ‘Dahongpao’ (DHP) is typically harvested when fully ripe, exhibiting a dark red color, high sweetness, and pleasant taste.. However, it remains uncertain whether the optimum harvesting time for its medicinal part (peel) aligns with that of the fruit.. The findings of the study indicated that the peel exhibited the highest concentration of total flavonoids (4.018 mg/g) during the middle stage of maturity.

Article Title: Exploring the mechanism of Huanglian ointment in alleviating wound healing after anal fistula surgery through metabolomics and proteomics
Article Snippet: Then, the obtained data were imported into the multivariate statistical analysis software SIMCA-P11.0 (Umeteics, Umea, Sweden) for principal component analysis (PCA) and Orthogonal Partial Least Squares-Discriminant Analysis (OPLS-DA).

Article Title: Tanshinone IIA reverses gefitinib resistance in EGFR-mutant lung cancer via inhibition of SREBP1-mediated lipogenesis.
Article Snippet: Funding information Guangdong Provincial Key Laboratory of Construction Foundation, Grant/Award Number: 2020B1212060034; National Natural Science Foundation of China, Grant/Award Numbers: 81973561, 82274146 Abstract Background and Aim: Gefitinib resistance is an urgent problem to be solved in the treatment of non-small cell lung cancer (NSCLC).. Tanshinone IIA (Tan IIA) is one of the main active components of Salvia miltiorrhiza, which exhibits significant antitumor effects.. The aim of this study is to explore the reversal effect of Tan IIA on gefitinib resistance in the epidermal growth factor receptor (EGFR)-mutant NSCLC and the underlying mechanism.

Software:

Article Title: Method development of amine‐containing metabolite analysis using di‐<i>tert</i>‐butyl dicarbonate derivatization coupled with liquid chromatography‐mass spectrometry
Article Snippet: .. The integrated area of the metabolite features was normalized to that of an IS, exported as CSV, and subjected to multivariate analysis using SIMCA-P + software (Version 14.0, Umertrics, Umea, Sweden). .. Statistical analysis was performed using GraphPad Prism (version 7.0, SD, USA).

Article Title: Shenfu injection alleviates lipopolysaccharide-induced liver injury in septic mice.
Article Snippet: The original data were subjected to baseline filtering, peak identification, integration, retention time correction and peak alignment with the Progenesis QI (waters Corporation, Milford, USA), and finally a data matrix including retention time, mass to charge ratio and peak intensity was obtained. .. Then, the obtained data were imported into the multivariate statistical analysis software SIMCA#P11.0 (Umeteics, Umea, Sweden) for principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA). ..

High Content Screening:

Article Title: GC-MS-based metabolome classification of sturgeon caviar and fish roe samples reveals unique caviar signatures, interspecies and gender variabilities.
Article Snippet: .. Multivariate data analysis was performed using unsupervised principal component analysis (PCA) and hierarchical cluster analysis (HCA), as well as supervised orthogonal partial least squares- discriminant analysis (OPLS-DA) with SIMCA 14.1 (Umetrics, Umea, Sweden). ..



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